Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition. Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry. We demonstrate the inhibition of hepatitis B virus core interactions with surfaces in vitro and the neutralization of infectious adeno-associated viruses exposed to human cells. We demonstrate this virus-trapping concept by engulfing hepatitis B virus core particles and adeno-associated viruses. The shell interior can be functionalized with virus-specific moieties in a modular fashion. We have created shells with molecular masses ranging from 43 to 925 MDa (8 to 180 subunits) and with internal cavity diameters of up to 280 nm. Programmable triangular building blocks constructed from DNA assemble with high yield into various shell objects with user-defined geometries and apertures. Here, we describe a programmable icosahedral canvas for the self-assembly of icosahedral shells that have viral trapping and antiviral properties. Nonetheless, effective technologies of this kind are still not available. Thank you for your understanding if you can read until now.Broad-spectrum antiviral platforms that can decrease or inhibit viral infection would alleviate many threats to global public health. It will be a loss not only for origami fans like me but also for your reputation. What a pity if you decide not to edit COS any longer. That's why everybody wants to use Windown or at least knows how to use Windown, which means popularity. He lets users access his product nearly freely, but he charges any company/organization/individual that want to make money from it. Do you know why it is so popular all over the world? From my point of view, this comes from strategy of Microsoft. However, I totally agree with you that they must PAY ROYALTY FEE IF THEY WANNA EARN MONEY FROM THESE such as in a musical performance, opera concert, etc.įinally, you can disagree with my opinion and do not publish any COS any more. Like a song, you can sing a song anytime anywhere without licence, right? Everyone around the world can sing a song without permission of composer, right? of course if they do not perform this for commercial purpose. 'I download this one but only for personal use' I swear so I don't understand what the problem is. I believe that most of people here will use that book personally.

We share the book, but we don't print it out for commercial use. Maybe you can be surprised when reading this but please listen to my explanation. However, I don't see any problem with our share of this book at this site. I would like to express my deep gratitude to your work and your contribution to origami community around the world. /lgbt/ - Lesbian, Gay, Bisexual, & Transgender.

Origami wasp 2.6 pdf